The gray color means that the item is locked by the game's UI. Probaly MultiCraft called the function to craft a potion and if you cancel it the items won't get unlocked again. It's the same as dragging an item from your iventory somwhere else but you would never drop it. The item will be grayed out as long as you drag it.
You need to relog (/reloadui alone won't help).
To test if it is MultiCraft:
Try to disable MultiCraft and do the same to craft your potions, and hit cancel then. Are the items still grayed out?
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